Article
Factors associated with blood mercury concentrations and their interactions with three glutathione S-transferase genes (GSTT1, GSTM1, and GSTP1): an exposure assessment study of typically developing Jamaican children.
BMC pediatrics - 4 Jan 2024
Zaman Sheikh Farzana, Samms-Vaughan Maureen, Saroukhani Sepideh, Bressler Jan, Hessabi Manouchehr, Grove Megan L, Pellington Sydonnie Shakespeare, Loveland Katherine A, Rahbar Mohammad H
Abstract excerpt
BACKGROUND: Jamaican soil is abundant in heavy metals including mercury (Hg). Due to availability and ease of access, fish is a traditional dietary component in Jamaica and a significant source of Hg exposure. Mercury is a xenobiotic and known neuro-toxicant that affects children's neurodevelopment. Human glutathione S-transferase (GST) genes, including GSTT1, GSTM1, and GSTP1, affect Hg conjugation and...
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