Article
Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide.
Toxicology letters - 10 Jun 2011
Huang Yu-Fang, Chen Mei-Lien, Liou Saou-Hsing, Chen Ming-Feng, Uang Shi-Nian, Wu Kuen-Yuh
Abstract excerpt
This study elucidates the association of acrylamide metabolites, N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA), N-acetyl-S-(1-carbamoyl-2-hydroxyethyl)-cysteine (GAMA2), and N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-cysteine (GAMA3) in urine with genetic polymorphisms of the metabolic enzymes cytochrome P450 2E1 (CYP2E1), microsomal epoxide hydrolase (mEH) in exon 3 and exon 4, glutathione transferase theta (GSTT1)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
