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Association between genetic variations in GSH-related and MT genes and low-dose methylmercury exposure in children and women of childbearing age: a pilot study.

Environmental research - 1 Aug 2020

Chan Peggy Hiu Ying, Chan Kathy Yuen Yee, Schooling Catherine Mary, Hui Lai Ling, Chan Michael Ho Ming, Li Albert Martin, Cheung Robert Chi Keung, Lam Hugh Simon

Abstract excerpt

BACKGROUND: Genetic variations in glutathione (GSH)-related and metallothionein (MT) genes, which are involved in producing enzymes in the methylmercury (MeHg) metabolism pathway, have been proposed as one of the reasons for the individual variability in MeHg toxicokinetics. OBJECTIVE: To investigate the impact of genetic variations in MT and GSH-related genes on the association of fish consumption with body...

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PMID: 32480025
DOI: 10.1016/j.envres.2020.109703

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