Article
Twitchy, the Drosophila orthologue of the ciliary gating protein FBF1/dyf-19, is required for coordinated locomotion and male fertility.
Biology open - 15 Aug 2021
Hodge Suzanne H, Watts Amy, Marley Richard, Baines Richard A, Hafen Ernst, MacDougall Lindsay K
Abstract excerpt
Primary cilia are compartmentalised from the rest of the cell by a ciliary gate comprising transition fibres and a transition zone. The ciliary gate allows the selective import and export of molecules such as transmembrane receptors and transport proteins. These are required for the assembly of the cilium, its function as a sensory and signalling centre and to maintain its distinctive composition. Certain motile...
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