Article
APOE genotype and cholesterol levels in lewy body dementia and Alzheimer disease: investigating genotype-phenotype effect on disease risk.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Dec 2006
Borroni Barbara, Grassi Mario, Costanzi Chiara, Archetti Silvana, Caimi Luigi, Padovani Alessandro
Abstract excerpt
BACKGROUND: APOE is the most recognized genetic risk factor for sporadic late-onset Alzheimer disease (AD). The role of APOE genotype in Lewy body dementia (LBD) is still unknown as well as the relationship between APOE genotype and cholesterol levels. OBJECTIVE: The objective of this study was to explore the association between APOE genotype and cholesterol levels in patients with LBD and those with AD. METHODS:...
Topics
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Cholesterol
- Genetic Variation
- Genotype
- Lewy Body Disease
- Models, Genetic
- Phenotype
- Risk Factors