Article
APOE genotype predicts AD and other dementia but not ischemic cerebrovascular disease.
Neurology - 23 Jan 2001
Frikke-Schmidt R, Nordestgaard B G, Thudium D, Moes Grønholdt M L, Tybjaerg-Hansen A
Abstract excerpt
BACKGROUND: The APOE polymorphism is an important modulator of plasma lipoproteins and a risk factor for AD. The hypothesis that APOE genotype, through its effect on lipoproteins, is a common risk factor for ischemic cerebrovascular disease (ICVD), AD, and other dementia (OD) was tested. METHODS: The authors genotyped 9241 individuals from the general population, 452 patients with ICVD and > or = 50% stenosis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.