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Article

Analysis of the genotoxicity of anthraquinone dyes in the mouse lymphoma assay.

Mutagenesis - 1 Jan 1991

Harrington-Brock K, Parker L, Doerr C, Cimino M C, Moore M M

Abstract excerpt

Despite their widespread use and potential for significant human exposure, genotoxicity data on anthraquinones and other dyes are limited. In this study, 16 anthraquinones and one azo dye (Solvent Red 1) were selected for testing using the thymidine kinase (tk) locus and micronucleus (MN) analysis in L5178Y/TK(+/-)-3.7.2C mouse lymphoma cells. Six of the dyes were from the same lot used in the NTP rodent...

Topics

Animals
Anthraquinones
Biotransformation
Coloring Agents
Lymphoma
Mice
Micronucleus Tests
Mutagenicity Tests
Mutation
Thymidine Kinase
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2038271
DOI: 10.1093/mutage/6.1.35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2038271-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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