Article
Common modifications of trimeric G proteins and ras protein: involvement of polyisoprenylation.
Science (New York, N.Y.) - 13 Jul 1990
Finegold A A, Schafer W R, Rine J, Whiteway M, Tamanoi F
Abstract excerpt
The heterotrimeric guanine nucleotide-binding regulatory proteins act at the inner surface of the plasma membrane to relay information from cell surface receptors to effectors inside the cell. These G proteins are not integral membrane proteins, yet are membrane associated. The processing and function of the gamma subunit of the yeast G protein involved in mating-pheromone signal transduction was found to be...
Topics
- Amino Acid Sequence
- Cell Membrane
- Cloning, Molecular
- Epitopes
- GTP-Binding Proteins
- Hemagglutinins, Viral
- Lovastatin
- Mevalonic Acid
- Molecular Sequence Data
- Mutation
- Oncogene Protein p21(ras)