Article
Yeast alpha-mating factor receptor and G-protein-linked adenylyl cyclase inhibition requires RAS2 and GPA2 activities.
Biochemical and biophysical research communications - 15 May 1992
Papasavvas S, Arkinstall S, Reid J, Payton M
Abstract excerpt
Saccharomyces cerevisiae expresses two RAS gene products (RAS1 and RAS2) highly homologous to mammalian p21ras which mediate glucose-stimulated cyclic-AMP formation. Mating pheromone inhibits RAS-linked adenylyl cyclase activation and this is dependent upon the alpha-factor receptor (STE2) and it...
Topics
- Adenylyl Cyclase Inhibitors
- Cyclic AMP
- Fungal Proteins
- GTP-Binding Proteins
- Genes, ras
- Genetic Complementation Test
- Genotype
- Kinetics
- Macromolecular Substances
- Mating Factor
- Peptides
- Phenotype
- Pheromones
- Receptors, Cell Surface
- Receptors, Mating Factor
- Receptors, Peptide
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins