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Article

Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein gamma subunit.

Molecular and cellular biology - 1 Jul 1994

Grishin A V, Weiner J L, Blumer K J

Abstract excerpt

Heterotrimeric guanine nucleotide-binding proteins (G proteins) consisting of alpha, beta, and gamma subunits mediate signalling between cell surface receptors and intracellular effectors in eukaryotic cells. To define signalling functions of G gamma subunits (STE18 gene product) involved in pheromone response and mating in the yeast Saccharomyces cerevisiae, we isolated and characterized dominant-negative STE18...

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Identifiers

PMID: 8007961
DOI: 10.1128/mcb.14.7.4571-4578.1994
PMCID: PMC358829

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Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein gamma subunit.PMID 8007961Read ↗

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