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Article

Association between PAI-1 Polymorphisms and Ischemic Stroke in a South Korean Case-Control Cohort.

International journal of molecular sciences - 28 Apr 2023

Choi Gun Ho, Cho Sung Hwan, An Hui Jeong, Park Han Sung, Lee Jeong Yong, Ko Eun Ju, Oh Seung Hun, Kim Ok Joon, Kim Nam Keun

Abstract excerpt

Stroke is the second leading cause of death in the world. Approximately 80% of strokes are ischemic in origin. Many risk factors have been linked to stroke, including an increased level of plasminogen activator inhibitor-1 (PAI-1). PAI-1 levels increase and remain elevated in blood during the acute phase of ischemic stroke, which can impair fibrinolytic activity, leading to coronary artery disease and arterial...

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Identifiers

PMID: 37175749
DOI: 10.3390/ijms24098041
PMCID: PMC10178745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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