Article
Fibrinolytic gene polymorphism and ischemic stroke.
Stroke - 1 Oct 2005
Jood Katarina, Ladenvall Per, Tjärnlund-Wolf Anna, Ladenvall Claes, Andersson Maria, Nilsson Staffan, Blomstrand Christian, Jern Christina
Abstract excerpt
BACKGROUND AND PURPOSE: The tissue-type plasminogen activator (tPA) -7351C>T and the plasminogen activator inhibitor type 1 (PAI-1) -675 4G>5G polymorphisms influence transcriptional activity. Both variants have been associated with myocardial infarction, with increased risk for the T and 4G allele, respectively. In this study we investigated the possible association between these polymorphisms, the respective...
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