Article
Protein C Promotor Haplotypes Associated with Large-Artery Atherosclerosis Stroke in Iranian Population.
Journal of molecular neuroscience : MN - 1 Oct 2021
Meshkani Seyed Elyas, Fasihi Ali, Badakhshan Fatemeh, Zahedi Mohmmadsaeid, Goudarzian Maryam, Ramazi Shahin
Abstract excerpt
Ischemic stroke (IS) is a complex disease regarding its risk factors; among those factors, genetics has an important role. Protein C (PC) is an important antithrombotic enzyme which its genetic variations disrupt the normal cascade of blood coagulation, resulting in thrombosis and increases the chance of stroke. Therefore, we aimed to investigate three single-nucleotide polymorphisms (SNPs) located in the core...
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