Angiopoietin-2 promoter haplotypes confer an increased risk of stroke in a Chinese Han population.

doi:10.1042/CS20090035

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Article

Angiopoietin-2 promoter haplotypes confer an increased risk of stroke in a Chinese Han population.

Clinical science (London, England : 1979) - 14 Sept 2009

Chen Jingzhou, Yu Hui, Song Weihua, Sun Kai, Song Yan, Lou Kejia, Yang Tao, Zhang Yinhui, Hui Rutai

Abstract excerpt

Angiopoietin-2 is an important mediator of angiogenesis, and we hypothesized that genetic variants of ANGPT2 (the gene encoding angiopoietin-2) would result in abnormal angiogenesis and contribute to stroke susceptibility. To test our hypothesis, we investigated the association of variants in the promoter of ANGPT2 with stroke in a multi-centre case-control study. We found that the C allele of rs3739390 conferred...

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PMID: 19341361
DOI: 10.1042/CS20090035

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ANGPT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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