Article
Association of genetic variants of fibrinolytic system with stroke and stroke subtypes.
Gene - 1 Mar 2012
Babu M Sai, Prabha T Surya, Kaul Subhash, Al-Hazzani Amal, Shafi Gowhar, Roy Sitara, Balakrishna N, Jyothy A, Munshi Anjana
Abstract excerpt
Genetic variants of tPA (PLAT) and PAI-1 genes have been suggested to be the risk factors for stroke. In the present case-control study we investigated the association of -7351C/T polymorphism (rs2020918) and I/D polymorphism of tPA gene and Insertion/deletion polymorphism (4G/5G) of PAI-1 gene with genetic predisposition to ischemic stroke. 516 stroke patients and 513, sex and age matched healthy controls were...
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