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Article

Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression.

The American journal of psychiatry - 1 Sept 2006

Zalsman Gil, Huang Yung-Yu, Oquendo Maria A, Burke Ainsley K, Hu Xian-Zhang, Brent David A, Ellis Steven P, Goldman David, Mann J John

Abstract excerpt

OBJECTIVE: The lower expressing allele of the serotonin transporter gene 5' promoter region (5-HTTLPR) polymorphism is reported to be associated with susceptibility to depression and suicidality in response to stressful life events. The authors examined the relationship of a triallelic 5-HTTLPR polymorphism to stressful life events, severity of major depression, and suicidality. METHOD: Mood disorder subjects...

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Source

Identifiers

PMID: 16946185
DOI: 10.1176/ajp.2006.163.9.1588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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