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Article

The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder.

Bipolar disorders - 1 Dec 2014

Benedetti Francesco, Riccaboni Roberta, Poletti Sara, Radaelli Daniele, Locatelli Clara, Lorenzi Cristina, Pirovano Adele, Smeraldi Enrico, Colombo Cristina

Abstract excerpt

OBJECTIVE: Bipolar disorder (BD) is associated with a higher risk of suicide and with worse early life stress. A serotonin (5-hydroxytryptamine; 5-HT) transporter-linked polymorphic region (5-HTTLPR) has been shown to influence the relationship between stress and the risk of attempting suicide in the general population, but has not been investigated in BD. METHODS: We studied 136 inpatients (93 females, 43 males)...

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Identifiers

PMID: 25219494
DOI: 10.1111/bdi.12250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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