Dual selection of a genetic switch by a single selection marker.

doi:10.1016/j.biosystems.2006.07.006

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Article

Dual selection of a genetic switch by a single selection marker.

Bio Systems - 1 Jan 2000

Nomura Yoko, Yokobayashi Yohei

Abstract excerpt

Forward engineering of synthetic genetic circuits in living cells is expected to deliver various applications in biotechnology and medicine and to provide valuable insights into the design principles of natural gene networks. However, lack of biochemical data and complexity of biological environment complicate rational design of such circuits based on quantitative simulation. Previously, we have shown that...

Topics

Computer Simulation
Escherichia coli
Evolution, Molecular
False Positive Reactions
Genetic Engineering
Models, Genetic
Models, Theoretical
Mutation
Phenotype
Plasmids
Promoter Regions, Genetic
Systems Biology

Source

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Identifiers

PMID: 16942834
DOI: 10.1016/j.biosystems.2006.07.006

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