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Article

Synthetic gene circuits: design with directed evolution.

Annual review of biophysics and biomolecular structure - 1 Jan 2007

Haseltine Eric L, Arnold Frances H

Abstract excerpt

Synthetic circuits offer great promise for generating insights into nature's underlying design principles or forward engineering novel biotechnology applications. However, construction of these circuits is not straightforward. Synthetic circuits generally consist of components optimized to function in their natural context, not in the context of the synthetic circuit. Combining mathematical modeling with directed...

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Identifiers

PMID: 17243895
DOI: 10.1146/annurev.biophys.36.040306.132600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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