Article
Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide.
The Journal of experimental medicine - 1 Jul 1990
Sibille C, Chomez P, Wildmann C, Van Pel A, De Plaen E, Maryanski J L, de Bergeyck V, Boon T
Abstract excerpt
Mutagen treatment of mouse tumor cell line P815 produces tum- variants that are rejected by syngeneic mice because they express new transplantation antigens. These tum- antigens are recognized by cytotoxic T lymphocytes (CTL) but induce no detectable antibody response. By transfecting P815 cell l...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Cosmids
- Epitopes
- Gene Expression
- Histocompatibility Antigens
- Mice
- Mice, Inbred DBA
- Molecular Sequence Data
- Mutation
- Peptide Biosynthesis
- Peptides
- Restriction Mapping