Article
Structure of the gene of tum- transplantation antigen P35B: presence of a point mutation in the antigenic allele.
The EMBO journal - 1 Apr 1990
Szikora J P, Van Pel A, Brichard V, André M, Van Baren N, Henry P, De Plaen E, Boon T
Abstract excerpt
Mutagen treatment of P815 tumour cells produces tum- variants that are rejected by syngeneic mice because they express new transplantation antigens. These 'tum-' antigens elicit a cytolytic T lymphocyte (CTL) response but no detectable antibody response. The DNA of tum- variant P35 was transfecte...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigens, Neoplasm
- Base Sequence
- Cell Line
- Chromosome Deletion
- Clone Cells
- Codon
- Cosmids
- Cytotoxicity, Immunologic
- Exons
