Article
Correlation of p53 gene mutation and expression of P53 protein in cholangiocarcinoma.
World journal of gastroenterology - 7 Aug 2006
Liu Xiao-Fang, Zhang Hao, Zhu Shi-Guang, Zhou Xian-Ting, Su Hai-Long, Xu Zheng, Li Shao-Jun
Abstract excerpt
AIM: To characterize the tumor suppressor gene p53 mutations and study the correlation of p53 gene mutation and the expression of P53 protein in cholangiocarcinoma. METHODS: A total of 36 unselected, frozen samples of cholangiocarcinoma were collected. p53 gene status (exon 5-8) and P53 protein were examined by automated sequencing and immunohistochemical staining, combined with the clinical parameters of...
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