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Article

A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus.

Diabetes - 1 Sept 2006

Ng Daniel P K, Placha Grzegorz, Choo Serena, Chia Kee-seng, Warram James H, Krolewski Andrzej S

Abstract excerpt

Previous investigations of the ACE gene as a susceptibility factor for diabetic nephropathy have primarily focused on its insertion/deletion (Ins/Del) polymorphism. In a departure from these earlier studies, we used three tagging markers (A-5466C, T-3892C, and Ins/Del) at the ACE locus to test for disease haplotype associations. A case-control study design was used where case subjects were type 2 diabetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16936219
DOI: 10.2337/db06-0496

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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