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Article

The angiotensin I-converting enzyme (ACE) locus is strongly associated with age and duration of diabetes in patients with type I diabetes.

Journal of diabetes and its complications - 1 Jan 2000

Hibberd M L, Millward B A, Demaine A G

Abstract excerpt

We have investigated the frequency of the angiotensin I-converting enzyme (ACE) insertion/ deletion (I/D) polymorphism in 249 patients with type I diabetes and 162 normal healthy controls. There was no significant difference in the frequency of ACE genotypes between those patients with diabetic nephropathy (n = 72) (nephropaths) compared to those with no proteinuria after 20 years duration of diabetes (n = 86)...

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Source

Identifiers

PMID: 9025006
DOI: 10.1016/1056-8727(95)00114-x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The angiotensin I-converting enzyme (ACE) locus is strongly associated with age and duration of diabetes in patients with type I diabetes.PMID 9025006Read ↗

Association of ACE gene polymorphism and diabetic nephropathy? The Diabetic Nephropathy Study Group.Semantic proximity Read ↗

The presence of allele D of angiotensin-converting enzyme polymorphism is associated with diabetic nephropathy in patients with less than 10 years duration of Type 2 diabetes.Semantic proximity Read ↗

Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control.Semantic proximity Read ↗

The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in the type-1 diabetics.Semantic proximity Read ↗

Lack of association between the insertion/deletion polymorphism of the angiotensin-converting-enzyme gene and diabetic nephropathy in IDDM patients.Semantic proximity Read ↗

ACE gene polymorphism and proliferative retinopathy in type 1 diabetes: results of a case-control study.Semantic proximity Read ↗

Nephropathy in type 1 diabetes is diminished in carriers of HLA-DRB1*04: the genetics of kidneys in diabetes (GoKinD) study.Semantic proximity Read ↗

[Does an association between angiotensin I converting enzyme gene polymorphism and the prevalence of diabetic nephropathy in patients with diabetes type II exist?].Semantic proximity Read ↗

Characteristics of Type 1 diabetes of over 50 years duration (the Golden Years Cohort).Semantic proximity Read ↗

Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, and diabetic retinopathy in subjects with IDDM and NIDDM.Semantic proximity Read ↗

Angiotensin I converting enzyme gene polymorphism and diabetic nephropathy in type II diabetes.Semantic proximity Read ↗

Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study.Semantic proximity Read ↗

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