Article
An angiotensin converting enzyme haplotype predicts survival in patients with end stage renal disease.
Human genetics - 1 Sept 2006
Wetmore James B, Johansen Kirsten L, Sen Saunak, Hung Adriana M, Lovett David H
Abstract excerpt
The renin-angiotensin system is implicated in the development of a variety of human diseases. Many studies have sought to characterize the clinical implications of polymorphisms in the angiotensin converting enzyme (ACE) gene. Given the high mortality rate of individuals on chronic hemodialysis (HD), we sought to investigate whether genetic diversity in the ACE gene correlates with mortality in this population....
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