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Article

Excess of DD homozygotes in haemodialysed patients with type II diabetes. The Diabetic Nephropathy Study Group.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Mar 1997

Schmidt S, Strojek K, Grzeszczak W, Bergis K, Ritz E

Abstract excerpt

The role of the insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE) gene in the genesis of diabetic nephropathy has been controversial. It has recently been proposed that progression occurs more rapidly in individuals with diabetic and non-diabetic renal disease who are homozygous for the D allele. We studied 658 patients with type II diabetes, 347 without diabetic nephropathy and 311 with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9075119
DOI: 10.1093/ndt/12.3.427

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Excess of DD homozygotes in haemodialysed patients with type II diabetes. The Diabetic Nephropathy Study Group.PMID 9075119Read ↗

The DD genotype of the ACE gene polymorphism is associated with progression of diabetic nephropathy to end stage renal failure in IDDM.Semantic proximity Read ↗

The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in the type-1 diabetics.Semantic proximity Read ↗

Angiotensin I converting enzyme gene polymorphism and diabetic nephropathy in type II diabetes.Semantic proximity Read ↗

Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study.Semantic proximity Read ↗

Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control.Semantic proximity Read ↗

[Angiotensin converting enzyme (ACE) gene polymorphism in a diabetic cohort and diabetic nephropathy].Semantic proximity Read ↗

Lack of association between the insertion/deletion polymorphism of the angiotensin-converting-enzyme gene and diabetic nephropathy in IDDM patients.Semantic proximity Read ↗

Increased frequency of angiotensin-converting enzyme DD genotype in patients with type 2 diabetes in Taiwan.Semantic proximity Read ↗

Angiotensin-converting enzyme gene I/D polymorphism and renal disease.Semantic proximity Read ↗

ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.Semantic proximity Read ↗

Association of the DD genotype and development of Japanese type 2 diabetic nephropathy.Semantic proximity Read ↗

The angiotensin-I converting enzyme gene I/D variation contributes to end-stage renal disease risk in Chinese patients with type 2 diabetes receiving hemodialysis.Semantic proximity Read ↗

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