Article
Diabetic nephropathy is associated with AGT polymorphism T235: results of a family-based study.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 1998
Rogus J J, Moczulski D, Freire M B, Yang Y, Warram J H, Krolewski A S
Abstract excerpt
Diabetic nephropathy is a serious and frequent complication of insulin-dependent diabetes mellitus (IDDM) that has a strong genetic component. Several case-control studies have reported conflicting results with regard to the role of angiotensinogen gene polymorphisms, specifically the M235T T allele, in the development of diabetic nephropathy. The primary limitation of the case-control approach is that bias may...
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