Article
ACE gene sequence and nucleotide variants in IgA nephropathy.
Singapore medical journal - 1 Nov 2011
Woo K T, Lau Y K, Chan C M, Zhao Y, Tan H B, Liu F E, Fook-Chong S, Wong K S
Abstract excerpt
INTRODUCTION: Association studies with single nucleotide polymorphisms (SNPs) have been contradictory. Haplotypes may be more helpful. With gene sequencing, all SNPs can be found for construction of haplotypes. METHODS: The ACE gene was sequenced in four healthy Chinese subjects and 20 patients with IgA nephropathy (IgAN) to observe if differences exist among SNPs and haplotypes. 20 patients on angiotensin...
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