Article
Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2005
Huertas-Vazquez Adriana, Aguilar-Salinas Carlos, Lusis Aldons J, Cantor Rita M, Canizales-Quinteros Samuel, Lee Jenny C, Mariana-Nuñez Lizzette, Riba-Ramirez Roopa-Metha Laura, Jokiaho Anne, Tusie-Luna Teresa, Pajukanta Päivi
Abstract excerpt
OBJECTIVE: To investigate the largely unknown genetic component of the common lipid disorder, familial combined hyperlipidemia (FCHL) in Mexicans, we analyzed the upstream transcription factor 1 (USF1) gene that was recently associated with FCHL and high triglycerides (TG) in Finns. We also analyzed the Mexican FCHL families for 26 microsatellite markers residing in the seven chromosomal regions on 2p25.1, 9p23,...
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