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Article

Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.

The Journal of biological chemistry - 25 May 1990

Pilz R B, Steglich C, Scheffler I E

Abstract excerpt

The ornithine decarboxylase (ODC)-deficient Chinese hamster ovary (CHO) cell line C55.7 has normal amounts of ODC mRNA with very low amounts of immunologically detectable ODC protein, suggesting a structural mutation; however, 5-azacytidine treatment leads to phenotypical reversion (Steglich, C., and Scheffler, I. E. (1985) Somat. Cell Mol. Genet. 11, 11-23). We have demonstrated by chemical cleavage a single...

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PMID: 1692838

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Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.PMID 1692838Read ↗

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