Article
Clinical implications of C-kit gene mutation in patients with large gastrointestinal stromal tumors.
Journal of gastroenterology and hepatology - 1 Oct 2006
Lin Shee-Chan, Liu Chien-Liang, Wang Tzang-In, Chang Wen-Shiung, Tzen Chin-Yuan, Huang Ming-Jer
Abstract excerpt
BACKGROUND AND AIM: To evaluate the clinical implications of C-kit gene mutation in patients with gastrointestinal stromal tumors (GIST) greater than 10 cm in size. METHODS: All cases of pathologically diagnosed GIST with positive CD117 immunostaining from one hospital were retrospectively reviewed. Tissue from the 25 patients with tumors greater than 10 cm in diameter were collected and DNA was extracted. Exons...
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