Article
[Dopamine system genes interaction and neurocognitive traits in patients with schizophrenia, their relatives and healthy controls from general population].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2006
Alfimova M V, Golimbet V E, Gritsenko I K, Lezheĭko T V, Abramova L I, Strel'tsova M A, Khlopina I V, Ebstein R
Abstract excerpt
To elucidate main effects of dopamine receptor D4 (DRD4) and cathecol-O-methyltransferase (COMT) genes as well as their interaction effect on neurocognitive traits, DRD4 gene polymorphisms (-809G/A, -521C/T) and the COMT gene Val158Met polymorphism, along with characteristics of verbal memory, executive functions and peculiarities of associative processes, have been studied in 150 patients with schizophrenia, 83...
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