Article
[The association of COMT and DRD2 gene polymorphisms with a cognitive ability to understand others in schizophrenic patients].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2013
Alfimova M V, Golimbet V E, Korovaĭtseva G I, Aksenova E V, Lezheĭko T V, Abramova L I, Kolesina N Iu, Anua I M, Savel'eva T M
Abstract excerpt
To evaluate a role of dopamine transmission in the theory of mind (ToM) dysfunction in schizophrenia, authors studied the association of ToM with COMT and DRD2 gene polymorphisms in 209 patients with schizophrenia and 172 healthy people. All subjects performed second-order false belief (FB2) and faux pas stories. The association between the COMT Val158Met polymorphism and performance on FB2 was found. The...
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