Article
[Genetic polymorphism of COMT in mental disorders].
Psychiatria polska - 1 Jan 2000
Tylec Aneta, Stryjecka-Zimmer Marta, Kucharska-Pietura Katarzyna
Abstract excerpt
Many neurobiochemical studies show abnormalities within dopaminergic neuropathways, particularly altered dopamine transmission in etiopathogenesis of mental disorders. Evaluation of genes associated with the dopaminergic system include five well known subtypes of dopaminergic receptors, dopamine transporter and enzymes associated with the synthesis and degradation of dopamine, such as tyrosine hydroxylase, dopa...
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