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Article

Identification of APOBEC3DE as Another Antiretroviral Factor from the Human APOBEC Family

15 Oct 2006

Abstract excerpt

A tandem arrayed gene cluster encoding seven cytidine deaminase genes is present on human chromosome 22. These are APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3DE, APOBEC3F, APOBEC3G, and APOBEC3H. Three of them, APOBEC3G, APOBEC3F, and APOBEC3B, block replication of human immunodeficiency virus type 1 (HIV-1) and many other retroviruses. In addition, APOBEC3A and APOBEC3C block intracellular retrotransposons and simian...

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Identifiers

PMID: 16920826
DOI: 10.1128/jvi.01123-06

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