Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targetome analysis of chaperone-mediated autophagy in cancer cells

1 Mar 2019

Abstract excerpt

Chaperone-mediated autophagy (CMA) is a lysosomal degradation pathway of select soluble proteins. Nearly one-third of the soluble proteins are predicted to be recognized by this pathway, yet only a minor fraction of this proteome has been identified as CMA substrates in cancer cells. Here, we undertook a quantitative multiplex mass spectrometry approach to study the proteome of isolated lysosomes in cancer cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30821613
DOI: 10.1080/15548627.2019.1586255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targetome analysis of chaperone-mediated autophagy in cancer cellsPMID 30821613Read ↗

Chaperone Mediated Autophagy Substrates and Components in CancerSemantic proximity Read ↗

The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cellsSemantic proximity Read ↗

The Complex Role of Chaperone-Mediated Autophagy in Cancer DiseasesSemantic proximity Read ↗

Chaperone-Mediated Autophagy and Its Implications for Neurodegeneration and CancerSemantic proximity Read ↗

Autophagy Regulation by the Translation Machinery and Its Implications in CancerSemantic proximity Read ↗

Canonical and Noncanonical ER Stress-Mediated Autophagy Is a Bite the Bullet in View of Cancer TherapySemantic proximity Read ↗

A curated census of autophagy-modulating proteins and small moleculesSemantic proximity Read ↗

Pros and Cons of Chaperone-Mediated Autophagy in Cancer BiologySemantic proximity Read ↗

A gene toolbox for monitoring autophagy transcriptionSemantic proximity Read ↗

Targeting Chaperone-Mediated Autophagy for Disease TherapySemantic proximity Read ↗

Puncta intended: connecting the dots between autophagy and cell stress networksSemantic proximity Read ↗

The Role of Chaperone-Mediated Autophagy in Cell Cycle Control and Its Implications in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.