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Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy

1 Sept 2022

Abstract excerpt

Macroautophagy is a bulk degradation system in which double membrane-bound structures called autophagosomes to deliver cytosolic materials to lysosomes. Autophagy promotes cellular homeostasis by selectively recognizing and sequestering specific targets, such as damaged organelles, protein aggregates, and invading bacteria, termed selective autophagy. We previously reported a type of selective autophagy,...

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Identifiers

PMID: 36103833
DOI: 10.1016/j.celrep.2022.111349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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