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Article

Novel applications of polymerase chain reaction to urinary nucleic acid analysis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Lichtenstein Anatoly V, Melkonyan Hovsep S, Tomei L David, Umansky Samuil R

Abstract excerpt

DNA fragments from cells that have died throughout the body not only appear in the bloodstream but also cross the kidney barrier into the urine. The relatively low molecular weight (150-200 bp) of this Transrenal DNA should be considered when deciding on methods of isolation and analysis. In particular, if polymerase chain reaction (PCR) is used for amplification and detection of specific sequences, then the...

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PMID: 16916260
DOI: 10.1385/1-59745-074-X:145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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