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Article

Transrenal DNA as a diagnostic tool: important technical notes.

Annals of the New York Academy of Sciences - 1 Jun 2004

Su Ying-Hsiu, Wang Mengjun, Block Timothy M, Landt Olfert, Botezatu Irina, Serdyuk Ol'ga, Lichtenstein Anatoly, Melkonyan Hovsep, Tomei L David, Umansky Samuil

Abstract excerpt

A small portion of DNA from apoptotic cells escapes complete degradation, appears in blood as oligonucleosomal-size fragments, is excreted in the urine, and can be used for diagnostic purposes. More detailed study revealed that transrenal DNA (Tr-DNA) belongs to a relatively low molecular-weight (150-250 bp) fraction, thereby requiring more careful attention to methods employed for purification and analysis. For...

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PMID: 15251944
DOI: 10.1196/annals.1318.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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