Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer.

The Journal of molecular diagnostics : JMD - 1 May 2004

Su Ying-Hsiu, Wang Mengjun, Brenner Dean E, Ng Alan, Melkonyan Hovsep, Umansky Samuil, Syngal Sapna, Block Timothy M

Abstract excerpt

Human urine has been shown to possess submicrogram per milliliter amounts of DNA. We show here that DNA isolated from human urine resolves into two size categories: the large species, greater than 1 kb, being predominantly cell associated and heterogeneous in size, and the smaller, between 150 to 250 bp, being mostly non-cell associated. We showed that the low molecular weight class of urine DNA is derived from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyps
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to DNA Mutational Analysis

Share to Neoplastic Cells, Circulating

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed Open full text

Identifiers

PMID: 15096565
DOI: 10.1016/S1525-1578(10)60497-7
PMCID: PMC1867475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human urine contains small, 150 to 250 nucleotide-sized, soluble DNA derived from the circulation and may be useful in the detection of colorectal cancer.PMID 15096565Read ↗

Detection of a K-ras mutation in urine of patients with colorectal cancer.Semantic proximity Read ↗

Detection of mutated K-ras DNA in urine, plasma, and serum of patients with colorectal carcinoma or adenomatous polyps.Semantic proximity Read ↗

Detection of mutant k-ras sequences in the urine of cancer patients.Semantic proximity Read ↗

Transrenal DNA as a diagnostic tool: important technical notes.Semantic proximity Read ↗

Genetic analysis of DNA excreted in urine: a new approach for detecting specific genomic DNA sequences from cells dying in an organism.Semantic proximity Read ↗

Removal of high-molecular-weight DNA by carboxylated magnetic beads enhances the detection of mutated K-ras DNA in urine.Semantic proximity Read ↗

Next-Generation Sequencing-Based Analysis of Urine Cell-Free mtDNA Reveals Aberrant Fragmentation and Mutation Profile in Cancer Patients.Semantic proximity Read ↗

Circulating Nucleic Acids and ApoptosisSemantic proximity Read ↗

Novel applications of polymerase chain reaction to urinary nucleic acid analysis.Semantic proximity Read ↗

Cell and Microvesicle Urine microRNA Deep Sequencing Profiles from Healthy Individuals: Observations with Potential Impact on Biomarker StudiesSemantic proximity Read ↗

Screening of human bladder tumors and urine sediments for the presence of H-ras mutations.Semantic proximity Read ↗

Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.