Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.

doi:10.1093/carcin/11.4.617

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Article

Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.

Carcinogenesis - 1 Apr 1990

Gerbracht U, Bursch W, Kraus P, Putz B, Reinacher M, Timmermann-Trosiener I, Schulte-Hermann R

Abstract excerpt

Phenotypically altered liver foci were produced in female Wistar rats by a single dose of N-nitrosomorpholine followed by promotion with phenobarbital (PB) for 20 or 28 weeks. Then treatment was changed to either hexachlorocyclohexane (HCH), or cyproterone acetate (CPA), or nafenopin (Naf) or clo...

Topics

Animals
Body Weight
Carcinogens
Cell Survival
Clofibrate
Cyproterone
Cyproterone Acetate
Female
Glutathione Transferase
Hexachlorocyclohexane
Liver
Liver Neoplasms, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nafenopin

Nitrosamines

Organ Size

Phenobarbital

Phenotype

Precancerous Conditions

Source

Open in PubMed

Identifiers

PMID: 1691053
DOI: 10.1093/carcin/11.4.617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1691053-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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