Article
Alterations of pancreatic hepatocytes in rats exposed to carcinogens.
The American journal of pathology - 1 Nov 1991
Rao M S, Subbarao V, Sato K, Reddy J K
Abstract excerpt
In this study, acute and chronic responses of pancreatic hepatocytes induced in F-344 rats by copper depletion-repletion protocol to certain hepatocarcinogens were examined. Administration of a single dose of tannic acid (subcutaneous), aflatoxin B1 (gavage), or lasiocarpine (intraperitoneally) caused characteristic nucleolar segregation in parenchymal cells of liver as well as in pancreatic hepatocytes. Chronic...
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