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Article

Sir3 C-terminal domain involvement in the initiation and spreading of heterochromatin.

Molecular and cellular biology - 1 Oct 2006

Liaw Hungjiun, Lustig Arthur J

Abstract excerpt

Heterochromatin is nucleated at a specific site and subsequently spreads into distal sequences through multiple interactions between modified histones and nonhistone proteins. In the yeast Saccharomyces cerevisiae, these nonhistone proteins include Sir2, Sir3, and Sir4. We have previously shown that loss of the C-terminal Rap1 domain containing Sir3 and Sir4 association sites can be overcome by tethering a...

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Identifiers

PMID: 16908543
DOI: 10.1128/MCB.01082-06
PMCID: PMC1636858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sir3 C-terminal domain involvement in the initiation and spreading of heterochromatin.PMID 16908543Read ↗

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