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Article

ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations.

Cytometry. Part B, Clinical cytometry - 15 Jul 2006

Zucchetto Antonella, Bomben Riccardo, Bo Michele Dal, Nanni Paola, Bulian Pietro, Rossi Francesca Maria, Del Principe Maria Ilaria, Santini Simone, Del Poeta Giovanni, Degan Massimo, Gattei Valter

Abstract excerpt

BACKGROUND: Expression of T cell specific zeta-associated protein 70 (ZAP-70) by B-cell chronic lymphocytic leukemia (B-CLL) cells, as investigated by flow cytometry, has both prognostic relevance and predictive power as surrogate for immunoglobulin heavy chain variable region (IgV(H)) mutations, although a standardization of the cytometric protocol is still lacking. METHODS: Flow cytometric analyses for ZAP-70...

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Share to Calibration
Share to Flow Cytometry
Share to Immunoglobulin Heavy Chains
Share to Immunoglobulin Variable Region
Share to Killer Cells, Natural
Share to Leukemia, Lymphocytic, Chronic, B-Cell
Share to T-Lymphocytes
Share to ZAP-70 Protein-Tyrosine Kinase

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Identifiers

PMID: 16906587
DOI: 10.1002/cyto.b.20127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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