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Investigating sex-specific associations of lipid traits with type 2 diabetes, glycemic traits and sex hormones using Mendelian randomization

9 Jan 2023

Abstract excerpt

BACKGROUND: Low-density lipoprotein (LDL)-cholesterol is positively associated with cardiovascular disease (CVD) and inversely associated with type 2 diabetes, which could detract from lipid modification. Here, we examined whether lipid traits potentially relevant to CVD aetiology, i.e. apolipoprotein B (apoB), triglycerides (TG) and lipoprotein(a) [Lp(a)] exhibited the same associations. We investigated...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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PMID: 36624450
DOI: 10.1186/s12933-022-01714-2

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