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Article

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis.

Diabetes care - 1 Feb 2021

Peters Tricia M, Holmes Michael V, Richards J Brent, Palmer Tom, Forgetta Vincenzo, Lindgren Cecilia M, Asselbergs Folkert W, Nelson Christopher P, Samani Nilesh J, McCarthy Mark I, Mahajan Anubha, Davey Smith George, Woodward Mark, O'Keeffe Linda M, Peters Sanne A E

Abstract excerpt

OBJECTIVE: Observational studies have demonstrated that type 2 diabetes is a stronger risk factor for coronary heart disease (CHD) in women compared with men. However, it is not clear whether this reflects a sex differential in the causal effect of diabetes on CHD risk or results from sex-specific residual confounding. RESEARCH DESIGN AND METHODS: Using 270 single nucleotide polymorphisms (SNPs) for type 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33277303
DOI: 10.2337/dc20-1137
PMCID: PMC7818328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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