Article
The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor.
Nature cell biology - 1 Sept 2006
Murata Takahiro, Delprato Anna, Ingmundson Alyssa, Toomre Derek K, Lambright David G, Roy Craig R
Abstract excerpt
The intracellular pathogen Legionella pneumophila avoids fusion with lysosomes and subverts membrane transport from the endoplasmic reticulum to create an organelle that supports bacterial replication. Transport of endoplasmic reticulum-derived vesicles to the Legionella-containing vacuole (LCV) requires bacterial proteins that are translocated into host cells by a type IV secretion apparatus called Dot/Icm....
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