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Article

Disturbed epidermal structure in mice with temporally controlled fatp4 deficiency.

The Journal of investigative dermatology - 1 Dec 2005

Herrmann Thomas, Gröne Hermann-Josef, Langbein Lutz, Kaiser Iris, Gosch Isabella, Bennemann Ute, Metzger Daniel, Chambon Pierre, Stewart Adrian Francis, Stremmel Wolfgang

Abstract excerpt

So far, little is known about the physiological role of fatty acid transport protein 4 (Fatp4, Slc27a4). Mice with a targeted disruption of the Fatp4 gene display features of a human neonatally lethal restrictive dermopathy with a hyperproliferative hyperkeratosis, a disturbed epidermal barrier, a flat dermal-epidermal junction, a reduced number of pilo-sebaceous structures, and a compact dermis, demonstrating...

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Identifiers

PMID: 16354193
DOI: 10.1111/j.0022-202X.2005.23972.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Disturbed epidermal structure in mice with temporally controlled fatp4 deficiency.PMID 16354193Read ↗

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