Article
Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice.
The Journal of biological chemistry - 25 May 2007
Moulson Casey L, Lin Meei-Hua, White J Michael, Newberry Elizabeth P, Davidson Nicholas O, Miner Jeffrey H
Abstract excerpt
FATP4 (fatty acid transport protein 4; also known as SLC27A4) is the most widely expressed member of a family of six long chain fatty acid transporters. FATP4 is highly expressed in enterocytes and has therefore been proposed to be a major importer of dietary fatty acids. Two independent mutations in Fatp4 cause mice to be born with thick, tight, shiny, "wrinkle-free" skin and a defective skin barrier; they die...
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