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Agpat6—a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium

1 Feb 2006

Abstract excerpt

In analyzing the sequence tags for mutant mouse embryonic stem (ES) cell lines in BayGenomics (a mouse gene-trapping resource), we identified a novel gene, 1-acylglycerol-3-phosphate O-acyltransferase (Agpat6), with sequence similarities to previously characterized glycerolipid acyltransferases. Agpat6's closest family member is another novel gene that we have provisionally designated Agpat8. Both Agpat6 and...

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PMID: 16449762
DOI: 10.1194/jlr.m500556-jlr200

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